Hmga1 | high mobility group AT-hook 1

GeneMGI:96160Synonyms: Hmgi, Hmgiy, +5 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsHmga1tm2b(EUCOMM)HmguhomozygoteEarly adultN/A * 
unresponsive to tactile stimuli1 supporting datasetHmga1tm2b(EUCOMM)HmguheterozygoteE18.5N/A * 
unresponsive to tactile stimuli1 supporting datasetHmga1tm2b(EUCOMM)HmguhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hmga1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Hmga1tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Hmga1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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