Hesx1 | homeobox gene expressed in ES cells

GeneMGI:96071Synonyms: HES-1, Rpx

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Digestive/alimentary Vision/eye Mortality/aging Craniofacial

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



anophthalmia	1 supporting dataset	Hesx1^em1(IMPC)J	homozygote	E18.5	N/A ^*
cleft palate	1 supporting dataset	Hesx1^em1(IMPC)J	homozygote	E18.5	N/A ^*
facial cleft	1 supporting dataset	Hesx1^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal head shape	1 supporting dataset	Hesx1^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal facial morphology	1 supporting dataset	Hesx1^em1(IMPC)J	homozygote	E18.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Hesx1^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hesx1.

Associated images

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Histopathology

There is no histopathology data found for Hesx1.

IMPC related publications

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External links

No external links available for Hesx1.

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*Hesx1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Hesx1^{tm220947(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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