Htt | huntingtin

GeneMGI:96067Synonyms: C430023I11Rik, IT15, +4 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Htt^em1(IMPC)H	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Htt^em1(IMPC)H	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Htt^em1(IMPC)H	heterozygote	Early adult	1.22x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Htt.

Associated images

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Histopathology

There is no histopathology data found for Htt.

IMPC related publications

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External links

No external links available for Htt.

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*Htt^em1(IMPC)H*	Exon Deletion	‌	mouse
*Htt^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Htt^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Htt^{tm48497(L1L2_gt2_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Htt^{tm48497(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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