Hc | hemolytic complement

GeneMGI:96031Synonyms: C5a, He, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	1 supporting dataset	Hc^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.28x10^-5
decreased fasting circulating glucose level	1 supporting dataset	Hc^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hc.

Associated images

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Histopathology

There is no histopathology data found for Hc.

IMPC related publications

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External links

No external links available for Hc.

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*Hc^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Hc^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hc^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hc^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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