H2-Eb2 | histocompatibility 2, class II antigen E beta2

GeneMGI:95902Synonyms: Ia-5, Ia5, +2 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

15Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating triglyceride level	1 supporting dataset	H2-Eb2^em1(IMPC)J	homozygote	Early adult	7.99x10^-5
decreased leukocyte cell number	1 supporting dataset	H2-Eb2^em1(IMPC)J	homozygote	Early adult	5.08x10^-5
thrombocytopenia	1 supporting dataset	H2-Eb2^em1(IMPC)J	homozygote	Early adult	4.28x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H2-Eb2.

Associated images

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Histopathology

There is no histopathology data found for H2-Eb2.

IMPC related publications

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External links

No external links available for H2-Eb2.

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*H2-Eb2^em1(IMPC)J*	Intra-exon deletion	‌	mouse
*H2-Eb2^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*H2-Eb2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*H2-Eb2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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