H13 | histocompatibility 13

GeneMGI:95886Synonyms: H-13, 1200006O09Rik, +4 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Skeleton Craniofacial Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral content1 supporting datasetH13tm1b(KOMP)WtsiheterozygoteEarly adult7.93x10-6 
preweaning lethality, complete penetrance1 supporting datasetH13tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased fasting circulating glucose level1 supporting datasetH13tm1b(KOMP)WtsiheterozygoteEarly adult1.57x10-6 
abnormal snout morphology1 supporting datasetH13tm1b(KOMP)WtsiheterozygoteEarly adult7.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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H13tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
H13tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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