Guk1 | guanylate kinase 1

GeneMGI:95871

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	2 supporting datasets	Guk1^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased leukocyte cell number	1 supporting dataset	Guk1^em1(IMPC)J	heterozygote	Early adult	5.8x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Guk1.

Associated images

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Histopathology

There is no histopathology data found for Guk1.

IMPC related publications

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External links

No external links available for Guk1.

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*Guk1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Guk1^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Guk1^{tm47512(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes