Grin2d | glutamate receptor, ionotropic, NMDA2D (epsilon 4)

GeneMGI:95823Synonyms: NMDAR2D, GluRepsilon4, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased startle reflex	1 supporting dataset	Grin2d^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.04x10^-5
increased bone mineral content	1 supporting dataset	Grin2d^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.03x10^-6
decreased heart weight	1 supporting dataset	Grin2d^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.24x10^-6
abnormal bone structure	1 supporting dataset	Grin2d^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.61x10^-5
decreased circulating triglyceride level	1 supporting dataset	Grin2d^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.32x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Grin2d.

Associated images

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Histopathology

There is no histopathology data found for Grin2d.

IMPC related publications

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External links

No external links available for Grin2d.

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*Grin2d^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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