Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system
16 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
5Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Grin2btm1e.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased mean platelet volume | 1 supporting dataset | Grin2btm1e.1(KOMP)Wtsi | heterozygote | Early adult | 7.21x10-5 | ||
| increased startle reflex | 1 supporting dataset | Grin2btm1e.1(KOMP)Wtsi | heterozygote | Early adult | 8.12x10-12 | ||
| decreased locomotor activity | 4 supporting datasets | Grin2btm1e.1(KOMP)Wtsi | heterozygote | Early adult | 1.06x10-7 | ||
| enlarged heart | 1 supporting dataset | Grin2btm1e.1(KOMP)Wtsi | heterozygote | Early adult | N/A * |
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External links
No external links available for Grin2b.
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| Grin2btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell mouse |
| Grin2btm1e.1(KOMP)Wtsi | Promoter excision from Targeted, non-conditional allele | | mouse |
| Grin2btm354689(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Grin2btm37380(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Grin2btm37380(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |