Grik5 | glutamate receptor, ionotropic, kainate 5 (gamma 2)

GeneMGI:95818Synonyms: GluRgamma2, KA2

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Nervous system Vision/eye Liver/biliary system Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased body length1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adult4.64x10-7 
decreased brain size1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adultN/A * 
small liver1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adult7.3x10-5 
cataract1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adult9.23x10-5 
abnormal eye morphology1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal brain morphology1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetGrik5em1(IMPC)MbphomozygoteEarly adult7.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Grik5em1(IMPC)MbpExon Deletionmouse
Grik5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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