Got2 | glutamatic-oxaloacetic transaminase 2, mitochondrial
Physiological systems
22 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Digestive/alimentary Nervous system Vision/eye Hematopoietic system Cardiovascular system Mortality/aging Craniofacial Renal/urinary system
11 No significant impact
2 Not tested
Data collections
Gene metrics:21Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cataract | 1 supporting dataset | Got2em1(IMPC)Mbp | heterozygote | Early adult | 9.23x10-5 | ||
| embryonic growth retardation | 1 supporting dataset | Got2em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal forebrain development | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal blood vessel morphology | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal vitelline vasculature morphology | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal midbrain development | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Got2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| small spleen | 2 supporting datasets | Got2em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Got2.
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| Got2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Got2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Got2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Got2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Got2tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Got2tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Got2tm3a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |