Got1 | glutamic-oxaloacetic transaminase 1, soluble
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging Cardiovascular system
12 No significant impact
7 Not tested
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| decreased leukocyte cell number | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.1x10-5 | ||
| decreased basophil cell number | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.21x10-5 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.48x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| prolonged RR interval | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.4x10-6 | ||
| decreased circulating glucose level | 1 supporting dataset | Got1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.03x10-5 |
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External links
No external links available for Got1.
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| Got1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Got1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Got1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |