Gna15 | guanine nucleotide binding protein, alpha 15

GeneMGI:95770Synonyms: Galpha15, G[a]15

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system

14 No significant impact

4 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vitreous body morphology1 supporting datasetGna15em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
abnormal skin morphology2 supporting datasetsGna15em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsGna15em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal uterus morphology1 supporting datasetGna15em1(IMPC)MbphomozygoteLate adultN/A * 
cataract1 supporting datasetGna15em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
microphthalmia1 supporting datasetGna15em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetGna15em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged testis1 supporting datasetGna15em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged ovary1 supporting datasetGna15em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetGna15em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gna15em1(IMPC)MbpExon Deletionmouse
Gna15tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gna15tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Gna15tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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