Ghr | growth hormone receptor

GeneMGI:95708Synonyms: GHBP, GHR/BP

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

5Associated diseases

Expression examined in:49Adult tissues

48Embryo tissues

Phenotypes

Phy. System:



increased circulating sodium level	1 supporting dataset	Ghr^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.74x10^-5
abnormal lens morphology	1 supporting dataset	Ghr^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.32x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ghr.

Associated images

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Histopathology

There is no histopathology data found for Ghr.

IMPC related publications

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External links

No external links available for Ghr.

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*Ghr^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ghr^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ghr^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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