Gfpt1 | glutamine fructose-6-phosphate transaminase 1
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging
15 No significant impact
6 Not tested
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| increased circulating HDL cholesterol level | 1 supporting dataset | Gfpt1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 8.38x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Gfpt1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 8.38x10-6 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Gfpt1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Gfpt1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Gfpt1tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * |
| | | | | | | | | | |
External links
No external links available for Gfpt1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Gfpt1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gfpt1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Gfpt1tm1c(EUCOMM)Wtsi | Wild type floxed exon (post-Flp) | | mouse |
| Gfpt1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |