Gda | guanine deaminase

GeneMGI:95678

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased T-helper cell number	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating fructosamine level	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.15x10^-5
decreased total body fat amount	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.87x10^-7
increased bone mineral density	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.33x10^-6
decreased circulating HDL cholesterol level	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.41x10^-7
decreased hematocrit	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.11x10^-5
increased lean body mass	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.39x10^-7
increased effector memory T-helper cell number	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.44x10^-8
decreased circulating serum albumin level	1 supporting dataset	Gda^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.99x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Gda.

Associated images

Loading...

Histopathology

There is no histopathology data found for Gda.

IMPC related publications

Loading...

External links

No external links available for Gda.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Gda^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

My Genes