Gch1 | GTP cyclohydrolase 1

GeneMGI:95675Synonyms: GTPCH, GTP-CH

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Gch1^em1(IMPC)H	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Gch1^em1(IMPC)H	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gch1.

Associated images

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Histopathology

There is no histopathology data found for Gch1.

IMPC related publications

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External links

No external links available for Gch1.

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*Gch1^em1(IMPC)H*	Exon Deletion	‌	mouse
*Gch1^em2(IMPC)H*	Exon Deletion	‌	mouse
*Gch1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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