Gc | vitamin D binding protein

GeneMGI:95669Synonyms: DBP, vitamin D binding protein

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



decreased circulating cholesterol level	1 supporting dataset	Gc^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.3x10^-7
decreased circulating triglyceride level	1 supporting dataset	Gc^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.44x10^-6
decreased circulating glucose level	1 supporting dataset	Gc^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.59x10^-6
decreased circulating HDL cholesterol level	1 supporting dataset	Gc^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1x10^-6
decreased circulating total protein level	1 supporting dataset	Gc^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.67x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Gc^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.72x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gc.

Associated images

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Histopathology

There is no histopathology data found for Gc.

IMPC related publications

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External links

No external links available for Gc.

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*Gc^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Gc^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Gc^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Gc^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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