Gbx1 | gastrulation brain homeobox 1

GeneMGI:95667Synonyms: Gbx-1

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Limbs/digits/tail Behavior/neurological Skeleton Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Allele:

Phy. System:



increased anxiety-related response	1 supporting dataset	Gbx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.62x10^-7
enlarged urinary bladder	1 supporting dataset	Gbx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased locomotor activity	7 supporting datasets	Gbx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.29x10^-7
increased circulating glucose level	1 supporting dataset	Gbx1^Gbx1	homozygote	Early adult	7.65x10^-10
rib fusion	1 supporting dataset	Gbx1^Gbx1	homozygote	Early adult	1.8x10^-5
decreased exploration in new environment	2 supporting datasets	Gbx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.09x10^-10
increased circulating alkaline phosphatase level	1 supporting dataset	Gbx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.57x10^-5
abnormal behavior	4 supporting datasets	Gbx1^Gbx1	homozygote	Early adult	2.35x10^-5
abnormal gait	1 supporting dataset	Gbx1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.71x10^-18
vertebral fusion	1 supporting dataset	Gbx1^Gbx1	homozygote	Early adult	1.8x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Gbx1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Gbx1.

IMPC related publications

Loading...

External links

No external links available for Gbx1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Gbx1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gbx1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gbx1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes