Gabra5 | gamma-aminobutyric acid type A receptor subunit alpha 5

GeneMGI:95617Synonyms: A230018I05Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal thymus morphology1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
small spleen1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
small testis1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetGabra5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gabra5em1(IMPC)CcpczExon Deletionmouse
Gabra5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gabra5tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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