Fut4 | fucosyltransferase 4

GeneMGI:95594Synonyms: 3-fucosyl-N-acetyl-lactosamine epitope, SSEA-1, +4 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological Skeleton Renal/urinary system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetFut4em1(IMPC)IcshomozygoteEarly adultN/A * 
decreased circulating creatinine level1 supporting datasetFut4em1(IMPC)IcshomozygoteEarly adult2.99x10-5 
decreased lean body mass2 supporting datasetsFut4em1(IMPC)IcshomozygoteEarly adult1.03x10-7 
abnormal freezing behavior1 supporting datasetFut4em1(IMPC)IcshomozygoteEarly adult4x10-5 
increased bone mineral content1 supporting datasetFut4em1(IMPC)IcshomozygoteEarly adult4.8x10-6 
increased total body fat amount2 supporting datasetsFut4em1(IMPC)IcshomozygoteEarly adult4.33x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fut4em1(IMPC)IcsDeletionmouse
Fut4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Fut4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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