Ftl1 | ferritin light polypeptide 1

GeneMGI:95589Synonyms: Ftl, L-ferritin

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Craniofacial

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal tooth morphology1 supporting datasetFtl1em1(IMPC)RbrchomozygoteLate adult2.42x10-14 
abnormal behavior1 supporting datasetFtl1em1(IMPC)RbrchomozygoteEarly adult2.52x10-6 
abnormal tooth morphology1 supporting datasetFtl1em1(IMPC)RbrchomozygoteEarly adult1.71x10-15 
abnormal circulating iron level1 supporting datasetFtl1em1(IMPC)RbrchomozygoteLate adult4.54x10-8 
decreased locomotor activity1 supporting datasetFtl1em1(IMPC)RbrchomozygoteEarly adult5.95x10-5 
increased red blood cell distribution width1 supporting datasetFtl1em1(IMPC)RbrchomozygoteEarly adult8.35x10-5 
short tibia1 supporting datasetFtl1em1(IMPC)RbrchomozygoteEarly adult5.8x10-8 
abnormal gait1 supporting datasetFtl1em1(IMPC)RbrchomozygoteEarly adult3.26x10-6 
thrombocytosis1 supporting datasetFtl1em1(IMPC)RbrchomozygoteLate adult6.74x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ftl1em1(IMPC)RbrcIndelmouse
Ftl1tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
es cell

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