Fth1 | ferritin heavy polypeptide 1

GeneMGI:95588Synonyms: H-ferritin, FHC, +2 more

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsFth1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetFth1tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetFth1tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetFth1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fth1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Fth1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Fth1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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