Cidec | cell death-inducing DFFA-like effector c
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Vision/eye Hearing/vestibular/ear
14 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 8.81x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.27x10-5 | ||
| decreased total body fat amount | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.89x10-5 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.88x10-5 | ||
| increased lean body mass | 2 supporting datasets | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.76x10-5 | ||
| abnormal optic disk morphology | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.59x10-6 | ||
| abnormal auditory brainstem response | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.74x10-5 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Cidectm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.39x10-6 |
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Human diseases caused by Cidec mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cidec.
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| Cidectm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Cidectm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Cidectm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Cidectm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Cidectm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |