Cidec | cell death-inducing DFFA-like effector c

GeneMGI:95585Synonyms: Fsp27, CIDE-3, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Vision/eye Hearing/vestibular/ear

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating alkaline phosphatase level	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.81x10^-5
increased circulating cholesterol level	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.27x10^-5
decreased total body fat amount	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.89x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.88x10^-5
increased lean body mass	2 supporting datasets	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.76x10^-5
abnormal optic disk morphology	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.59x10^-6
abnormal auditory brainstem response	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.74x10^-5
increased fasting circulating glucose level	1 supporting dataset	Cidec^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.39x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cidec.

Associated images

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Histopathology

There is no histopathology data found for Cidec.

IMPC related publications

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External links

No external links available for Cidec.

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*Cidec^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Cidec^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Cidec^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cidec^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cidec^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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