Fpgs | folylpolyglutamyl synthetase

GeneMGI:95576

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased startle reflex	2 supporting datasets	Fpgs^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	2.97x10^-7
increased IgM level	1 supporting dataset	Fpgs^{tm1a(EUCOMM)Hmgu}	heterozygote	Early adult	1.24x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Fpgs^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fpgs.

Associated images

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Histopathology

There is no histopathology data found for Fpgs.

IMPC related publications

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External links

No external links available for Fpgs.

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*Fpgs^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Fpgs^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fpgs^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Fpgs^{tm26672(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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