Fos | FBJ osteosarcoma oncogene
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system Craniofacial
16 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Fosem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Fosem1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| increased total body fat amount | 2 supporting datasets | Fosem1(IMPC)Mbp | heterozygote | Early adult | 2.28x10-5 | ||
| abnormal facial morphology | 1 supporting dataset | Fosem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Fosem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| hemorrhage | 1 supporting dataset | Fosem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Fosem1(IMPC)Mbp | heterozygote | Early adult | 6.62x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | Fosem1(IMPC)Mbp | heterozygote | Early adult | 1.91x10-5 |
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External links
No external links available for Fos.
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| Fosem1(IMPC)Mbp | Whole-gene deletion | | mouse |
| Fostm380306(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |