Fgf7 | fibroblast growth factor 7

GeneMGI:95521Synonyms: Kgf, Keratinocyte growth factor

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Limbs/digits/tail Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

abnormal tail length1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult8.48x10-6 
mydriasis1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult2.41x10-5 
abnormal iris morphology1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult8.01x10-5 
abnormal startle reflex1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult1.61x10-11 
impaired pupillary reflex1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult1.83x10-7 
impaired righting response1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult4.47x10-6 
abnormal placement of pupils1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult4.09x10-5 
irregularly shaped pupil1 supporting datasetFgf7tm1e.1(EUCOMM)HmguhomozygoteEarly adult6.39x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fgf7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Fgf7tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
mouse
Fgf7tm1e.1(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse

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