Fgf4 | fibroblast growth factor 4

GeneMGI:95518Synonyms: Hst1, kFGF, +3 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetFgf4em1(IMPC)HheterozygoteEarly adult6.32x10-5 
embryonic lethality prior to organogenesis1 supporting datasetFgf4em1(IMPC)HhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetFgf4em1(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fgf4em1(IMPC)HExon Deletionmouse
Fgf4tm281631(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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