Fgf2 | fibroblast growth factor 2

GeneMGI:95516Synonyms: Fgf-2, Fgfb, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

16 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased circulating total protein level1 supporting datasetFgf2tm1b(EUCOMM)WtsihomozygoteEarly adult3.7x10-5 
increased circulating serum albumin level1 supporting datasetFgf2tm1b(EUCOMM)WtsihomozygoteEarly adult1.78x10-6 
limb grasping1 supporting datasetFgf2tm1b(EUCOMM)WtsihomozygoteEarly adult9.41x10-7 
abnormal retina morphology1 supporting datasetFgf2tm1b(EUCOMM)WtsihomozygoteEarly adult1.56x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fgf2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fgf2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Fgf2tm413(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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