Fbn2 | fibrillin 2
Physiological systems
19 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Craniofacial Cardiovascular system Renal/urinary system
6 No significant impact
5 Not tested
Data collections
Gene metrics:42Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| vertebral fusion | 1 supporting dataset | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | 5.23x10-6 | ||
| increased bone mineral content | 1 supporting dataset | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | 4.19x10-6 | ||
| abnormal nail morphology | 2 supporting datasets | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | 1.71x10-15 | ||
| abnormal autopod morphology | 2 supporting datasets | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | 1.74x10-15 | ||
| abnormal optic disk morphology | 1 supporting dataset | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | 5.15x10-5 | ||
| abnormal kidney morphology | 2 supporting datasets | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | N/A * | ||
| abnormal heart weight | 1 supporting dataset | Fbn2em1(IMPC)Rbrc | homozygote | Late adult | 4.98x10-7 | ||
| abnormal liver morphology | 2 supporting datasets | Fbn2em1(IMPC)Rbrc | homozygote | Early adult | N/A * | ||
| abnormal heart morphology | 2 supporting datasets | Fbn2em1(IMPC)Rbrc | homozygote | Late adult | N/A * | ||
| abnormal liver morphology | 2 supporting datasets | Fbn2em1(IMPC)Rbrc | homozygote | Late adult | N/A * |
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External links
No external links available for Fbn2.
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| Fbn2em1(IMPC)Rbrc | Indel | | mouse |