Fabp1 | fatty acid binding protein 1, liver

GeneMGI:95479Synonyms: L-FABP, Fabpl

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased leukocyte cell number	1 supporting dataset	Fabp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.37x10^-8
decreased monocyte cell number	1 supporting dataset	Fabp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1x10^-4
increased circulating bilirubin level	1 supporting dataset	Fabp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.28x10^-6
decreased large unstained cell number	2 supporting datasets	Fabp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.43x10^-6
decreased lymphocyte cell number	1 supporting dataset	Fabp1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.88x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fabp1.

Associated images

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Histopathology

There is no histopathology data found for Fabp1.

IMPC related publications

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External links

No external links available for Fabp1.

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*Fabp1^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Fabp1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Fabp1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Fabp1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fabp1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Fabp1^{tm2(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell

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