Erbb2 | erb-b2 receptor tyrosine kinase 2

GeneMGI:95410Synonyms: Neu oncogene, HER-2, +6 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



preweaning lethality, complete penetrance	1 supporting dataset		Erbb2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Erbb2.

Associated images

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Histopathology

There is no histopathology data found for Erbb2.

IMPC related publications

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External links

No external links available for Erbb2.

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*Erbb2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Erbb2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Erbb2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Erbb2^{tm96(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Erbb2^{tm96(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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