Egr1 | early growth response 1

GeneMGI:95295Synonyms: NGF1-A, Zfp-6, +11 more

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hematopoietic system Skeleton Mortality/aging

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

60Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal hindbrain development	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	E9.5	N/A ^*
male infertility	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	Early adult	N/A ^*
short tibia	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	heterozygote	Early adult	8.95x10^-6
small uterus	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	Early adult	N/A ^*
increased lymphocyte cell number	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	heterozygote	Early adult	1.7x10^-5
absent seminal vesicle	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	Early adult	N/A ^*
abnormal midbrain development	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	E9.5	N/A ^*
abnormal optic disk morphology	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	Early adult	2.34x10^-5
preweaning lethality, incomplete penetrance	3 supporting datasets	Egr1^{tm1b(NCOM)Mfgc}	homozygote	Early adult	N/A ^*
abnormal forebrain development	1 supporting dataset	Egr1^{tm1b(NCOM)Mfgc}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Egr1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Egr1.

IMPC related publications

Loading...

External links

No external links available for Egr1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Egr1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Egr1^{tm1a(NCOM)Mfgc}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Egr1^{tm1b(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Egr1^{tm214497(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes