Dpp4 | dipeptidylpeptidase 4

GeneMGI:94919Synonyms: Cd26, THAM, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hearing/vestibular/ear Hematopoietic system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



improved glucose tolerance	1 supporting dataset	Dpp4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.07x10^-6
abnormal auditory brainstem response	2 supporting datasets	Dpp4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.52x10^-6
decreased lymphocyte cell number	1 supporting dataset	Dpp4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.41x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dpp4.

Associated images

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Histopathology

There is no histopathology data found for Dpp4.

IMPC related publications

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External links

No external links available for Dpp4.

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*Dpp4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Dpp4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Dpp4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dpp4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Dpp4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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