Ddc | dopa decarboxylase

GeneMGI:94876Synonyms: Aadc, aromatic L-amino acid decarboxylase

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Skeleton Craniofacial Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Ddc^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Ddc^{em1(IMPC)Hmgu}	heterozygote	Early adult	2.96x10^-6
abnormal tooth morphology	1 supporting dataset	Ddc^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.96x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ddc.

Associated images

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Histopathology

There is no histopathology data found for Ddc.

IMPC related publications

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External links

No external links available for Ddc.

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*Ddc^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Ddc^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell

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