Acadvl | acyl-Coenzyme A dehydrogenase, very long chain

GeneMGI:895149Synonyms: VLCAD

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetAcadvlem1(IMPC)HhomozygoteEarly adult1.76x10-7 
impaired glucose tolerance1 supporting datasetAcadvlem1(IMPC)HhomozygoteEarly adult5.76x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Acadvlem1(IMPC)HIndelmouse
Acadvlem2(IMPC)HIndelmouse
Acadvltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Acadvltm448743(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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