Col9a3 | collagen, type IX, alpha 3

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hearing/vestibular/ear Hematopoietic system

11 No significant impact

6 Not tested

Gene metrics:9Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating triglyceride level1 supporting datasetCol9a3em1(IMPC)TcphomozygoteEarly adult6.48x10-5 
enlarged lymph nodes1 supporting datasetCol9a3em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal auditory brainstem response3 supporting datasetsCol9a3em1(IMPC)TcphomozygoteEarly adult2.77x10-9 
abnormal seminal vesicle morphology1 supporting datasetCol9a3em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetCol9a3em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased body length1 supporting datasetCol9a3em1(IMPC)TcphomozygoteEarly adult8.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Col9a3em1(IMPC)TcpExon Deletionmouse
Col9a3tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Col9a3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Col9a3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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