Ranbp2 | RAN binding protein 2

GeneMGI:894323Synonyms: A430087B05Rik

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Mortality/aging

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

4Associated diseases

Expression examined in:73Adult tissues

30Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Ranbp2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Ranbp2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Ranbp2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Ranbp2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Ranbp2^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Ranbp2^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Ranbp2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ranbp2.

Associated images

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Histopathology

There is no histopathology data found for Ranbp2.

IMPC related publications

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External links

No external links available for Ranbp2.

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*Ranbp2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ranbp2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ranbp2^{tm187953(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Ranbp2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ranbp2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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