Ranbp2 | RAN binding protein 2
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Mortality/aging
19 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Ranbp2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| small testis | 1 supporting dataset | Ranbp2tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| enlarged epididymis | 1 supporting dataset | Ranbp2tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Ranbp2tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ranbp2tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Ranbp2tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal epididymis morphology | 1 supporting dataset | Ranbp2tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 50% (1/2) | 0.19% (1/533) |
| blood | heterozygote | Section images | 50% (1/2) | 0% (0/17) |
| bone marrow | heterozygote | Section images | 100% (2/2) | 0% (0/22) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | Section images | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | Section images | 100% (1/1) | 7.75% (22/284) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
External links
No external links available for Ranbp2.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ranbp2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Ranbp2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Ranbp2tm187953(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Ranbp2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ranbp2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |