Tacr3 | tachykinin receptor 3

GeneMGI:892968Synonyms: Tac3r, Nk3r, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Adipose tissue Vision/eye Behavior/neurological Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content2 supporting datasetsTacr3em1(IMPC)JhomozygoteEarly adult1.19x10-6 
decreased bone mineral density1 supporting datasetTacr3em1(IMPC)JhomozygoteEarly adult4.96x10-5 
female infertility1 supporting datasetTacr3em1(IMPC)JhomozygoteEarly adultN/A * 
decreased grip strength1 supporting datasetTacr3em1(IMPC)JhomozygoteEarly adult4.61x10-6 
abnormal cornea morphology1 supporting datasetTacr3em1(IMPC)JhomozygoteEarly adult2.9x10-5 
increased total body fat amount1 supporting datasetTacr3em1(IMPC)JhomozygoteEarly adult1.85x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tacr3em1(IMPC)JExon Deletionmouse

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