Cpa1 | carboxypeptidase A1, pancreatic

GeneMGI:88478Synonyms: 0910001L12Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetCpa1em1(IMPC)MarchomozygoteEarly adult1.09x10-6 
increased leukocyte cell number1 supporting datasetCpa1em1(IMPC)MarchomozygoteEarly adult9.35x10-6 
decreased red blood cell distribution width1 supporting datasetCpa1em1(IMPC)MarchomozygoteEarly adult1.31x10-5 
increased mean corpuscular hemoglobin1 supporting datasetCpa1em1(IMPC)MarchomozygoteEarly adult1.97x10-10 
increased lymphocyte cell number1 supporting datasetCpa1em1(IMPC)MarchomozygoteEarly adult9.42x10-12 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cpa1em1(IMPC)MarcDeletionmouse
Cpa1tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cpa1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cpa1tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Cpa1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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