Cp | ceruloplasmin

GeneMGI:88476Synonyms: D3Ertd555e

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

52Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.06x10^-8
decreased circulating iron level	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.16x10^-8
hypoalgesia	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.08x10^-5 ^**
decreased mean corpuscular hemoglobin	2 supporting datasets	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	0
decreased mean corpuscular volume	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	0
decreased hemoglobin content	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.86x10^-10
increased heart weight	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.37x10^-5
abnormal sleep behavior	1 supporting dataset	Cp^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.27x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

** Significant with a threshold of 1x10^-3, check the Pain Sensitivity page for more information.

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* This parameter was manually assessed for significance.

** Significant with a threshold of 1x10^-3, check the Pain Sensitivity page for more information.

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lacZ Expression

No adult expression data available for Cp.

Associated images

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Histopathology

There is no histopathology data found for Cp.

IMPC related publications

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External links

No external links available for Cp.

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*Cp^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cp^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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