Cox4i1 | cytochrome c oxidase subunit 4I1

GeneMGI:88473Synonyms: Cox4a, COXIV, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:41Adult tissues
29Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetCox4i1tm1.1(KOMP)VlcgheterozygoteEarly adult1.49x10-5 
preweaning lethality, complete penetrance3 supporting datasetsCox4i1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetCox4i1tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetCox4i1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cox4i1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Cox4i1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Cox4i1tm455699(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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