Col11a1 | collagen, type XI, alpha 1
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Growth/size/body region Limbs/digits/tail Digestive/alimentary Mortality/aging Craniofacial Cardiovascular system
15 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
9Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal tail morphology | 1 supporting dataset | Col11a1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Col11a1em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal facial morphology | 1 supporting dataset | Col11a1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| abnormal limb morphology | 1 supporting dataset | Col11a1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| protruding tongue | 1 supporting dataset | Col11a1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| cleft palate | 1 supporting dataset | Col11a1em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| increased heart left ventricle size | 1 supporting dataset | Col11a1em1(IMPC)Bay | heterozygote | Early adult | 3.05x10-5 |
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External links
No external links available for Col11a1.
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| Col11a1em1(IMPC)Bay | Exon Deletion | | mouse |
| Col11a1em2(IMPC)Wtsi | Exon Deletion | | mouse |
| Col11a1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Col11a1tm44767(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Col11a1tm44767(L1L2_st1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |