Col11a1 | collagen, type XI, alpha 1

GeneMGI:88446Synonyms: C530001D20Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Digestive/alimentary Mortality/aging Craniofacial Cardiovascular system

15 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
9Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal tail morphology1 supporting datasetCol11a1em1(IMPC)BayhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsCol11a1em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal facial morphology1 supporting datasetCol11a1em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal limb morphology1 supporting datasetCol11a1em1(IMPC)BayhomozygoteE18.5N/A * 
protruding tongue1 supporting datasetCol11a1em1(IMPC)BayhomozygoteE18.5N/A * 
cleft palate1 supporting datasetCol11a1em1(IMPC)BayhomozygoteE18.5N/A * 
increased heart left ventricle size1 supporting datasetCol11a1em1(IMPC)BayheterozygoteEarly adult3.05x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Col11a1em1(IMPC)BayExon Deletionmouse
Col11a1em2(IMPC)WtsiExon Deletionmouse
Col11a1tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Col11a1tm44767(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Col11a1tm44767(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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