Cnp | 2',3'-cyclic nucleotide 3' phosphodiesterase

GeneMGI:88437Synonyms: Cnp-1, CNPase, +1 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

16 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity1 supporting datasetCnptm1b(EUCOMM)WtsihomozygoteEarly adult2.01x10-6 
decreased thigmotaxis1 supporting datasetCnptm1b(EUCOMM)WtsihomozygoteEarly adult3x10-6 
abnormal behavior1 supporting datasetCnptm1b(EUCOMM)WtsihomozygoteEarly adult3x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cnptm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
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Cnptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Cnptm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cnptm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cnptm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Cnptm79(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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