Chd1 | chromodomain helicase DNA binding protein 1
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging Craniofacial
11 No significant impact
5 Not tested
Data collections
Gene metrics:11Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Chd1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased grip strength | 2 supporting datasets | Chd1tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.98x10-6 | ||
| anophthalmia | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| abnormal maxilla morphology | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.58x10-5 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.08x10-6 | ||
| abnormal embryo size | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | heterozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| decreased red blood cell distribution width | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.07x10-5 | ||
| abnormal eye morphology | 1 supporting dataset | Chd1tm1b(KOMP)Wtsi | heterozygote | E12.5 | N/A * |
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External links
No external links available for Chd1.
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