Cd68 | CD68 antigen
Physiological systems
15 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
13 No significant impact
9 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Cd68em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal locomotor behavior | 1 supporting dataset | Cd68em1(IMPC)Bay | heterozygote | Early adult | 5.25x10-5 |
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Human diseases caused by Cd68 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cd68.
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| Cd68em1(IMPC)Bay | Exon Deletion | | mouse |
| Cd68tm1(EGFP/cre/ERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Cd68tm1(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Cd68tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Cd68tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cd68tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |