Cd22 | CD22 antigen

GeneMGI:88322Synonyms: Lyb8, Lyb-8

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating cholesterol level	1 supporting dataset	Cd22^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.77x10^-5
increased startle reflex	1 supporting dataset	Cd22^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.76x10^-5
increased monocyte cell number	1 supporting dataset	Cd22^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.45x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cd22.

Associated images

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Histopathology

There is no histopathology data found for Cd22.

IMPC related publications

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External links

No external links available for Cd22.

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*Cd22^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Cd22^{tm115136(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cd22^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cd22^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cd22^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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