C4b | complement C4B (Chido blood group)
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Growth/size/body region Behavior/neurological
17 No significant impact
5 Not tested
Data collections
Gene metrics:2Significant phenotypes
9Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased lean body mass | 1 supporting dataset | C4bem1(IMPC)H | homozygote | Early adult | 5.25x10-6 | ||
| increased freezing behavior | 1 supporting dataset | C4bem1(IMPC)H | homozygote | Early adult | 3.72x10-6 |
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Human diseases caused by C4b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for C4b.
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| C4bem1(IMPC)H | Exon Deletion | | mouse |
| C4bem2(IMPC)H | Exon Deletion | | mouse |
| C4btm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |