C1qa | complement component 1, q subcomponent, alpha polypeptide

GeneMGI:88223Synonyms: C1q

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

3Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes



increased circulating chloride level	1 supporting dataset	C1qa^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.35x10^-5
decreased circulating glucose level	1 supporting dataset	C1qa^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.4x10^-6
decreased blood urea nitrogen level	1 supporting dataset	C1qa^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.44x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for C1qa.

Associated images

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Histopathology

There is no histopathology data found for C1qa.

IMPC related publications

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External links

No external links available for C1qa.

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*C1qa^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*C1qa^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*C1qa^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*C1qa^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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