Bcl3 | B cell leukemia/lymphoma 3

GeneMGI:88140Synonyms: Bcl-3

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Craniofacial

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal snout morphology	1 supporting dataset	Bcl3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.95x10^-5
thrombocytopenia	1 supporting dataset	Bcl3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.56x10^-5
increased spleen weight	1 supporting dataset	Bcl3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.33x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bcl3.

Associated images

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Histopathology

There is no histopathology data found for Bcl3.

IMPC related publications

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External links

No external links available for Bcl3.

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*Bcl3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Bcl3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Bcl3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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